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DR. ALTHEA PDRN Reju 5000 Cream (20g)

£21.50

Key Ingredients:

Also known as PDRN, Sodium DNA is a sodium salt of DNA, extracted from wild salmon milt, that encourages skin regeneration and elasticity by increasing cell proliferation in fibroblasts, which are responsible for skin collagen production.
Shop all PDRN
Centella asiatica, also known as cica, is a K-beauty staple prized for calming, soothing and hydrating stressed or sensitive skin while supporting the moisture barrier.
Shop all Centella
Hyaluronic acid is a humectant that holds many times its weight in water, drawing moisture into the upper layers of skin to keep it hydrated, plump and dewy.
Shop all Hyaluronic Acid

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PDRN Reju 5000 Cream (20g)

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£21.50

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About the DR. ALTHEA PDRN Reju 5000 Cream (20g)

Meet the cream that brings one of aesthetics' most talked-about ingredients home. PDRN (Polydeoxyribonucleotide), represented here as Sodium DNA at 5000ppm, is a highly purified active derived from salmon DNA that has long been celebrated in professional skincare for its ability to visibly revitalise tired, stressed skin. Dr. Althea's Reju 5000 Cream harnesses this powerhouse to help your skin look plumper, smoother and noticeably more rested over time.

What makes this formula feel considered rather than gimmicky is the supporting cast around that hero. Centella Asiatica Leaf Water forms a calming, skin-soothing base while sh-Oligopeptide-1, a biotechnology-derived peptide analogue of EGF (Epidermal Growth Factor), works alongside PDRN to help the skin's surface appear firmer and more youthful. Aureobasidium Pullulans Ferment, a gentle biome-derived ferment, adds another layer of skin-conditioning support, helping to reinforce the skin's natural resilience.

A trio of Hyaluronic Acid forms, including Hyaluronic Acid, Sodium Hyaluronate and Hydrolyzed Hyaluronic Acid, delivers multi-depth moisture: the lighter, hydrolysed form absorbs quickly into the upper layers while the larger molecules sit at the surface to lock hydration in. Panthenol (provitamin B5) and Tocopherol (vitamin E) round out the formula with softening and antioxidant support.

Despite its richly active composition, the Reju 5000 Cream has a lightweight, non-greasy finish that sinks in without heaviness. It layers beautifully, making it adaptable for different skin needs: use a lighter layer on oilier days or build it up when your skin is calling for deeper comfort. Suitable for Cherubs of all skin types, particularly those whose skin is looking dull, fatigued or in need of a visible firmness reset.

It's Skin Cupid approved because...

...Dr. Althea has concentrated PDRN at a meaningful 5000ppm dose in a genuinely skin-first formula, pairing it with biotechnology-led actives like sh-Oligopeptide-1 and a multi-weight Hyaluronic Acid system that most creams at this price point simply don't bother with.

At a glance:

Suits all skin types, especially those with dull, fatigued or loss-of-firmness concerns
Delivers PDRN (Sodium DNA) at 5000ppm to visibly revitalise and plump the skin's appearance
Pairs PDRN with sh-Oligopeptide-1 (a biotechnology-derived EGF analogue peptide) for visible firming support
Soothes and calms with a Centella Asiatica Leaf Water base
Hydrates at multiple depths with three forms of Hyaluronic Acid
Strengthens the skin's natural resilience with Aureobasidium Pullulans Ferment
Absorbs with a lightweight, non-greasy finish that can be layered to suit your skin's needs

Ingredients in DR. ALTHEA PDRN Reju 5000 Cream (20g)

Sodium DNA (PDRN): A highly purified polydeoxyribonucleotide active, present at 5000ppm. Beloved in professional skincare, it helps the skin's surface appear visibly plumper, more revitalised and smoother with consistent use.

SH-Oligopeptide-1: A biotechnology-derived peptide that mimics the action of Epidermal Growth Factor (EGF). It works to support the skin's surface in looking firmer and more youthful over time.

Centella Asiatica Leaf Water: A soothing botanical base derived from tiger grass, known for its calming properties. It helps to reduce the appearance of redness and supports a more even, comfortable complexion.

Hyaluronic Acid / Sodium Hyaluronate / Hydrolyzed Hyaluronic Acid: Three complementary weights of this iconic humectant, working at different depths. Together they draw moisture into the skin, helping it look dewy, plump and well-hydrated throughout the day.

Panthenol: Provitamin B5, a well-loved skin-softener that helps to improve the feeling of smoothness and comfort, particularly in stressed or sensitised skin.

Aureobasidium Pullulans Ferment: A biome-derived ferment that conditions and helps reinforce the skin's natural resilience, supporting a healthier-looking surface.

Beta-Sitosterol: A plant-derived sterol that helps to soothe the skin's appearance and supports a calmer, more even-looking complexion.

Tocopherol: Vitamin E, a natural antioxidant that helps to protect the skin's surface from the visible effects of environmental stressors while contributing to a softer, smoother feel.

Aqua (Water), Glycerin, Centella Asiatica Leaf Water, Panthenol, Butylene Glycol, Dicaprylyl Ether, 1,2-Hexanediol, Vinyl Dimethicone, Caprylyl Methicone, Hydrogenated Polydecene, Pentylene Glycol, Dicaprylyl Carbonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium DNA, Dimethiconol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Olivate, Aminomethyl Propanediol, Sorbitan Olivate, Glyceryl Acrylate/Acrylic Acid Copolymer, Xanthan Gum, Ethylhexylglycerin, Sodium Hyaluronate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Phytate, Tocopherol, Aureobasidium Pullulans Ferment, Caprylic/Capric Triglyceride, Beta-Sitosterol, Hydrogenated Lecithin, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, sh-Oligopeptide-1

*Ingredients are subject to change at the manufacturer's discretion.

How to use DR. ALTHEA PDRN Reju 5000 Cream (20g)

After cleansing, toning and applying your serum, finish with the Reju 5000 Cream as the final step in your routine.

1. Dispense a small amount (a pea-sized amount to a fingertip-sized scoop is usually plenty for a full face application).
2. Warm the cream between your fingertips for a moment to help it melt into the skin more easily.
3. Apply across the face and neck using gentle pressing and patting motions, working outwards from the centre of the face.
4. For lighter coverage on warmer days or oilier skin, use a smaller amount. For drier or more dehydrated skin, build up a second layer once the first has absorbed.
5. Use morning and/or evening as part of your regular routine.

Caution: If any irritation develops, stop using and consult a doctor if necessary. Do not use on damaged skin or open wounds. Keep out of reach of children. Avoid contact with eyes. Do not ingest. Store in a cool, dry place away from direct sunlight.